Integrated high-throughput analysis identifies super enhancers in metastatic castration-resistant prostate cancer

• Main Authors: Jie Zeng (Author), Jiahong Chen (Author), Maozhang Li (Author), Chuanfan Zhong (Author), Zezhen Liu (Author), Yan Wang (Author), Yuejiao Li (Author), Funeng Jiang (Author), Shumin Fang (Author), Weide Zhong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Metastatic castration-resistant prostate cancer (mCRPC) is a highly aggressive stage of prostate cancer, and non-mutational epigenetic reprogramming plays a critical role in its progression. Super enhancers (SE), epigenetic elements, are involved in multiple tumor-promoting signaling pat...