Molecularly Imprinted Polymeric Nanoparticles as Drug Delivery System for Tenofovir, an Acyclic Nucleoside Phosphonate Antiviral

• Autori principali: Thomas Mathieu (Autore), Patrick Favetta (Autore), Luigi A. Agrofoglio (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2024-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

A molecularly imprinted polymer of Tenofovir (1), an FDA-approved acyclic nucleoside phosphonate with antiviral activity, was synthesized using a non-covalent approach. A pre-polymerization complex was formed between (1) and DMAEMA and in-house synthetic <i>N1</i>-[(2-methacryloyloxy)eth...