Development and Validation of a Capillary Zone Electrophoresis-Tandem Mass Spectrometry Method for Simultaneous Quantification of Eight β-Lactam Antibiotics and Two β-Lactamase Inhibitors in Plasma Samples

• Egile Nagusiak: Ivana Cizmarova (Egilea), Peter Mikus (Egilea), Martin Svidrnoch (Egilea), Juraj Piestansky (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Monitoring plasma concentrations of β-lactam antibiotics is crucial, particularly in critically ill patients, where variations in concentrations can lead to treatment failure or adverse events. Standardized antimicrobial regimens may not be effective for all patients, especially in special groups wi...