Potential of hydroxybenzoic acids from Graptopetalum paraguayense for inhibiting of herpes simplex virus DNA polymerase - metabolome profiling, molecular docking and quantum-chemical analysis

• Main Authors: Nadezhda Todorova (Author), Miroslav Rangelov (Author), Ivayla Dincheva (Author), Ilian Badjakov (Author), Venelin Enchev (Author), Nadezhda Markova (Author)
• Format: Book
• Published: Pensoft Publishers, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

According to our previous investigation the total methanol extract from Graptopetalum paraguayense E. Walther demonstrates a significant inhibitory effect on herpes simplex virus type 1 (HSV-1). To clarify what causes this inhibitory activity on HSV-1, a metabolic profile of the plant was performed....