Identification and characterization of related substances in EVT-401 by hyphenated LC-MS techniques

• Main Authors: Binan Zhu (Author), Yuting Lu (Author), Leilin Chen (Author), Binbin Yu (Author), Yuexin Liu (Author), Min Song (Author), Taijun Hang (Author)
• Format: Book
• Published: Elsevier, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A sensitive and selective method was developed for the separation and characterization of related substances (RSs) in EVT-401 by hyphenated LC-MS techniques. Complete separation of the RSs was achieved with an Inertsil ODS-SP column (250 mm×4.6 mm, 5 µm) by linear gradient elution using a mobile pha...