Pitavastatin Is a Highly Potent Inhibitor of T-Cell Proliferation

• Main Authors: Linda Voss (Author), Karina Guttek (Author), Annika Reddig (Author), Annegret Reinhold (Author), Martin Voss (Author), Luca Simeoni (Author), Burkhart Schraven (Author), Dirk Reinhold (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Repositioning of approved drugs is an alternative time- and cost-saving strategy to classical drug development. Statins are 3-hydroxy-3-methylglutaryl-CoA (HMG CoA) reductase inhibitors that are usually used as cholesterol-lowering medication, and they also exhibit anti-inflammatory effects. In the...