Pimozide and Imipramine Blue Exploit Mitochondrial Vulnerabilities and Reactive Oxygen Species to Cooperatively Target High Risk Acute Myeloid Leukemia

Pimozide and Imipramine Blue Exploit Mitochondrial Vulnerabilities and Reactive Oxygen Species to Cooperatively Target High Risk Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a heterogeneous disease with a high relapse rate. Cytokine receptor targeted therapies are therapeutically attractive but are subject to resistance-conferring mutations. Likewise, targeting downstream signaling pathways has been difficult. Recent success in the develo...

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Bibliographic Details
Main Authors: Zhengqi Wang (Author), Tian Mi (Author), Heath L. Bradley (Author), Jonathan Metts (Author), Himalee Sabnis (Author), Wandi Zhu (Author), Jack Arbiser (Author), Kevin D. Bunting (Author)
Format: Book
Published: MDPI AG, 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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