Limited Sampling Strategy for Determination of Ibrutinib Plasma Exposure: Joint Analyses with Metabolite Data

Limited Sampling Strategy for Determination of Ibrutinib Plasma Exposure: Joint Analyses with Metabolite Data

Therapeutic drug monitoring of ibrutinib is based on the area under the curve of concentration vs. time (AUC<sub>IBRU</sub>) instead of trough concentration (C<sub>min,ss</sub>) because of a limited accumulation in plasma. Our objective was to identify a limited sampling stra...

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Main Authors: Félicien Le Louedec (Author), Fanny Gallais (Author), Fabienne Thomas (Author), Mélanie White-Koning (Author), Ben Allal (Author), Caroline Protin (Author), Loïc Ysebaert (Author), Étienne Chatelut (Author), Florent Puisset (Author)
Format: Book
Published: MDPI AG, 2021-02-01T00:00:00Z.
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3rd Floor Main Library

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