P53 Mutation at Codon 249 is Uncommon in Neonatal Kotb Disease Biliary Atresia

• Main Authors: Magd A. Kotb (Author), Ayda K. Kelany (Author), Sherif Shehata (Author), Gamal El Tagy (Author), Sherif Kaddah (Author), Nahla I. Sabry (Author), Ahmed A. Elhaddad (Author), Radwa Shamma (Author)
• Format: Book
• Published: Cairo University, Faculty of Medicine, Department of Pediatrics, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hepatocellular carcinoma (HCC) is known to result from aflatoxin B1 that induces p53 mutation at codon 249. Aflatoxins are also known to cause The Kotb disease Biliary atresia (BA) variant which is characterized by congenital aflatoxicosis B1 in neonates with null glutathione S transfera...