P53 Mutation at Codon 249 is Uncommon in Neonatal Kotb Disease Biliary Atresia

• Hauptverfasser: Magd A. Kotb (Verfasst von), Ayda K. Kelany (Verfasst von), Sherif Shehata (Verfasst von), Gamal El Tagy (Verfasst von), Sherif Kaddah (Verfasst von), Nahla I. Sabry (Verfasst von), Ahmed A. Elhaddad (Verfasst von), Radwa Shamma (Verfasst von)
• Format: Buch
• Veröffentlicht: Cairo University, Faculty of Medicine, Department of Pediatrics, 2024-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background: Hepatocellular carcinoma (HCC) is known to result from aflatoxin B1 that induces p53 mutation at codon 249. Aflatoxins are also known to cause The Kotb disease Biliary atresia (BA) variant which is characterized by congenital aflatoxicosis B1 in neonates with null glutathione S transfera...