A Novel Ex Vivo Model of Aortic Valve Calcification. A Preliminary Report

• Main Authors: Arsenii Zabirnyk (Author), Maria del Mar Perez (Author), Marc Blasco (Author), Kåre-Olav Stensløkken (Author), Miguel D. Ferrer (Author), Carolina Salcedo (Author), Jarle Vaage (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: No pharmacological treatment exists to prevent or stop the calcification process of aortic valves causing aortic stenosis. The aim of this study was to develop a robust model of induced calcification in whole aortic valve leaflets which could be suitable for studies of the basic mechanis...