Evaluation of the Efficacy of PARP Inhibitors in Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-Analysis

• Main Authors: Kan Wu (Author), Jiayu Liang (Author), Yanxiang Shao (Author), Sanchao Xiong (Author), Shuyang Feng (Author), Xiang Li (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Poly(ADP-ribose) polymerase (PARP) inhibitors have breakthrough designations for metastatic castration-resistant prostate cancer (mCRPC). We performed a meta-analysis of current clinical trials to evaluate the efficacy of PARP inhibitors in mCRPC patients based on their genetic status.Me...