Difference in the Dissolution Behaviors of Tablets Containing Polyvinylpolypyrrolidone (PVPP) Depending on Pharmaceutical Formulation After Storage Under High Temperature and Humid Conditions

• Главные авторы: Yoh Takekuma (Автор), Haruka Ishizaka (Автор), Masato Sumi (Автор), Yuki Sato (Автор), Mitsuru Sugawara (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Предметы: article
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PURPOSE. Storage under high temperature and humid conditions has been reported to decrease the dissolution rate for some kinds of tablets containing polyvinylpolypyrrolidone (PVPP) as a disintegrant. The aim of this study was to elucidate the properties of pharmaceutical formulations with PVPP that...