RUNX1 promotes angiogenesis in colorectal cancer by regulating the crosstalk between tumor cells and tumor associated macrophages

• Main Authors: Xuxue Guo (Author), Haonan Zhang (Author), Chengcheng He (Author), Kaiwen Qin (Author), Qiuhua Lai (Author), Yuxin Fang (Author), Qianhui Chen (Author), Weize Li (Author), Yiqing Wang (Author), Xinke Wang (Author), Aimin Li (Author), Side Liu (Author), Qingyuan Li (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Colorectal cancer (CRC) is a common malignancy worldwide. Angiogenesis and metastasis are the critical hallmarks of malignant tumor. Runt-related transcription factor 1 (RUNX1), an efficient transcription factor, facilitates CRC proliferation, metastasis and chemotherapy resistance. We aime...