Ultra-high-performance liquid chromatography for the determination of exenatide in monkey plasma by tandem quadrupole mass spectrometry

• Main Authors: Jin-Feng Zhang (Author), Chun-Jie Sha (Author), Yu Sun (Author), Yun-Yun Gai (Author), Ji-Ye Sun (Author), Jiang-Bin Han (Author), Xin Shao (Author), Chun-Na Sha (Author), You-Xin Li (Author), Wan-Hui Liu (Author)
• Format: Book
• Published: Elsevier, 2013-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A highly sensitive ultra-high-performance liquid chromatographicâtandem mass spectrometry (UPLC/MS/MS) method was developed for the quantification of the synthetic peptide drug of exenatide in monkey plasma. Sample preparation was carried out by solid-phase extraction (SPE), and bivalirudin was used...