Chromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants

• Auteurs principaux: Yao Xiao (Auteur), Shengbo Jiao (Auteur), Miao He (Auteur), Da Lin (Auteur), Huanyan Zuo (Auteur), Jiahao Han (Auteur), Yonghua Sun (Auteur), Gang Cao (Auteur), Zhi Chen (Auteur), Huan Liu (Auteur)
• Format: Livre
• Publié: Nature Publishing Group, 2022-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Genome-wide association studies (GWASs) are the most widely used method to identify genetic risk loci associated with orofacial clefts (OFC). However, despite the increasing size of cohort, GWASs are still insufficient to detect all the heritability, suggesting there are more associations u...