Heme Oxygenase Induction Attenuates TNF-α-Induced Hypertension in Pregnant Rodents

• Main Authors: Eric M George (Author), Jacob M Stout (Author), David E Stec (Author), Joey P Granger (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pre-eclampsia is a hypertensive disorder of pregnancy initiated by placental insufficiency and chronic ischemia. In response, several pathways activated in the placenta are responsible for the maternal syndrome, including increased production of the anti-angiogenic protein, sFlt-1, and inflammatory...