Guanabenz inhibits alveolar bone resorption in a rat model of periodontitis

• Main Authors: Ryujiro Muramatsu (Author), Takuma Sato (Author), Kazunori Hamamura (Author), Ken Miyazawa (Author), Atsushi Takeguchi (Author), Masako Tabuchi (Author), Akifumi Togari (Author), Shigemi Goto (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increase of sympathetic activity has been known to exacerbate osteoporosis through promotion of bone resorption. However, it is largely unknown about involvement of sympathetic activity in exacerbation of periodontitis. In this study, we investigated whether α2-adrenergic receptor (α2-AR) agonist gu...