A pharmacodynamic investigation into the efficacy of osteoprotegerin during aseptic inflammation

• Main Authors: Curl Linda (Author), Barker Christopher (Author), Dreyer Craig (Author), Sampson Wayne (Author)
• 格式: 图书
• 出版: Sciendo, 2012-11-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: Osteoprotegerin (OPG), as an osteoclast antagonist, limits mineralised tissue resorption under physiological conditions. Previous work investigating OPG in a rat periodontal ligament (PDL) ankylosis model found no inhibitory effect on osteoclasts when OPG was administered at a dosage of...