The application of single cell gel electrophoresis or comet assay to human monitoring studies

• Main Authors: Valverde Mahara (Author), Ostrosky-Wegman Patricia (Author), Rojas Emilio (Author), Fortoul Teresa (Author), Meneses Fernando (Author), Ramírez Matiana (Author), Díaz-Barriga Fernando (Author), Cebrian Mariano (Author)
• Format: Book
• Published: Instituto Nacional de Salud Pública, 1999-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative. Material and methods. This technique detects principally single strand breaks as well as alkali-labile and repair-retarded sites. Results. Herein we pres...