The application of single cell gel electrophoresis or comet assay to human monitoring studies
Objective. In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative. Material and methods. This technique detects principally single strand breaks as well as alkali-labile and repair-retarded sites. Results. Herein we pres...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
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Instituto Nacional de Salud Pública,
1999-01-01T00:00:00Z.
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| 001 | doaj_55fe3dcaa8be4b51a850d177a37e5e79 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Valverde Mahara |e author |
| 700 | 1 | 0 | |a Ostrosky-Wegman Patricia |e author |
| 700 | 1 | 0 | |a Rojas Emilio |e author |
| 700 | 1 | 0 | |a Fortoul Teresa |e author |
| 700 | 1 | 0 | |a Meneses Fernando |e author |
| 700 | 1 | 0 | |a Ramírez Matiana |e author |
| 700 | 1 | 0 | |a Díaz-Barriga Fernando |e author |
| 700 | 1 | 0 | |a Cebrian Mariano |e author |
| 245 | 0 | 0 | |a The application of single cell gel electrophoresis or comet assay to human monitoring studies |
| 260 | |b Instituto Nacional de Salud Pública, |c 1999-01-01T00:00:00Z. | ||
| 500 | |a 0036-3634 | ||
| 520 | |a Objective. In the search of new human genotoxic biomarkers, the single cell gel electrophoresis assay has been proposed as a sensible alternative. Material and methods. This technique detects principally single strand breaks as well as alkali-labile and repair-retarded sites. Results. Herein we present our experience using the single cell gel electrophoresis assay in human population studies, both occupationally and environmentally exposed. Conclusions. We discuss the assay feasibility as a genotoxic biomarker. | ||
| 546 | |a EN | ||
| 546 | |a ES | ||
| 690 | |a biological markers | ||
| 690 | |a single cell gel electrophoresis assay | ||
| 690 | |a Public aspects of medicine | ||
| 690 | |a RA1-1270 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Salud Pública de México, Vol 41, Iss suppl.2, Pp S109-S113 (1999) | |
| 787 | 0 | |n http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0036-36341999000800007 | |
| 787 | 0 | |n https://doaj.org/toc/0036-3634 | |
| 856 | 4 | 1 | |u https://doaj.org/article/55fe3dcaa8be4b51a850d177a37e5e79 |z Connect to this object online. |