CD8low T cells expanded following acute Trypanosoma cruzi infection and benznidazole treatment are a relevant subset of IFN-γ producers.

• Main Authors: Alessandro Marins- (Author), Bianca Perdigão Olivieri (Author), Rafaella Ferreira-Reis (Author), Juliana de Meis (Author), Andrea Alice Silva (Author), Tania C de Araújo-Jorge (Author), Joseli Lannes-Vieira (Author), Vinicius Cotta- (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD8 T cells are regarded as pivotal players in both immunoprotection and immunopathology following Trypanosoma cruzi infection. Previously, we demonstrated the expansion of CD8+ T lymphocytes in the spleen of T. cruzi-infected mice under treatment with benznidazole (N-benzyl-2-nitroimidazole acetami...