In Vitro Enhanced Skin Permeation and Retention of Imiquimod Loaded in β-Cyclodextrin Nanosponge Hydrogel

• Main Authors: Monica Argenziano (Author), Adam Haimhoffer (Author), Chiara Bastiancich (Author), László Jicsinszky (Author), Fabrizio Caldera (Author), Francesco Trotta (Author), Sara Scutera (Author), Daniela Alotto (Author), Mara Fumagalli (Author), Tiziana Musso (Author), Carlotta Castagnoli (Author), Roberta Cavalli (Author)
• Format: Book
• Published: MDPI AG, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Imiquimod (IMQ) is an immune response modifier clinically used for the treatment of various topical diseases. However, its poor aqueous solubility and skin penetration capability make the topical delivery of IMQ a challenging task. This work aims at developing a nanomedicine-based topical formulatio...