A Novel Berberine-Glycyrrhizic Acid Complex Formulation Enhanced the Prevention Effect to Doxorubicin-Induced Cardiotoxicity by Pharmacokinetic Modulation of Berberine in Rats

• Main Authors: Shichang Zhang (Author), Yiwei Zhao (Author), Liangjun Tan (Author), Sheng Wu (Author), Qing Zhang (Author), Boxin Zhao (Author), Guofeng Li (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Developing a new drug delivery system is one of the useful approaches to overcome the limited use of berberine (BBR) to enhance its absorption and bioavailability. We prepared a novel berberine-glycyrrhizic acid (BBR-GL) complex formulation to increase the plasma concentration and bioavailability of...