A Novel Berberine-Glycyrrhizic Acid Complex Formulation Enhanced the Prevention Effect to Doxorubicin-Induced Cardiotoxicity by Pharmacokinetic Modulation of Berberine in Rats

• Egile Nagusiak: Shichang Zhang (Egilea), Yiwei Zhao (Egilea), Liangjun Tan (Egilea), Sheng Wu (Egilea), Qing Zhang (Egilea), Boxin Zhao (Egilea), Guofeng Li (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Developing a new drug delivery system is one of the useful approaches to overcome the limited use of berberine (BBR) to enhance its absorption and bioavailability. We prepared a novel berberine-glycyrrhizic acid (BBR-GL) complex formulation to increase the plasma concentration and bioavailability of...