Probable Drug Interaction Between Etanercept and Cyclosporine Resulting in Clinically Unexpected Low Trough Concentrations: First Case Report

• Main Authors: Haini Wen (Author), Dongping Chen (Author), Jiaqian Lu (Author), Zheng Jiao (Author), Bin Chen (Author), Bin Zhang (Author), Chaoyang Ye (Author), Li Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Preclinical studies have shown that anti-cytokine therapies could alter drug dispositions through affecting cytochrome P450 synthesis; however, evidence and case reports evaluating clinical relevance of this interaction are scarce. This is the first reported case of interaction between cyclosporine...