Dual Tumor Suppressor and Tumor Promoter Action of Sirtuins in Determining Malignant Phenotype

• Asıl Yazarlar: Vincenzo Carafa (Yazar), Lucia Altucci (Yazar), Angela Nebbioso (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Sirtuins (SIRTs), class III histone deacetylases, are differentially expressed in several human cancers, where they display both oncogenic and tumor-suppressive properties depending on cellular context and experimental conditions. SIRTs are involved in many important biological processes and play a...