Latent TGFβ-binding proteins 1 and 3 protect the larval zebrafish outflow tract from aneurysmal dilatation

• मुख्य लेखकों: Maryline Abrial (लेखक), Sandeep Basu (लेखक), Mengmeng Huang (लेखक), Vincent Butty (लेखक), Asya Schwertner (लेखक), Spencer Jeffrey (लेखक), Daniel Jordan (लेखक), Caroline E. Burns (लेखक), C. Geoffrey Burns (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2022-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Aortic root aneurysm is a common cause of morbidity and mortality in Loeys-Dietz and Marfan syndromes, where perturbations in transforming growth factor beta (TGFβ) signaling play a causal or contributory role, respectively. Despite the advantages of cross-species disease modeling, animal models of...