Predicting transcription factor binding sites using DNA shape features based on shared hybrid deep learning architecture

• Autori principali: Siguo Wang (Autore), Qinhu Zhang (Autore), Zhen Shen (Autore), Ying He (Autore), Zhen-Heng Chen (Autore), Jianqiang Li (Autore), De-Shuang Huang (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The study of transcriptional regulation is still difficult yet fundamental in molecular biology research. Recent research has shown that the double helix structure of nucleotides plays an important role in improving the accuracy and interpretability of transcription factor binding sites (TFBSs). Alt...