Unlocking the potential of established products: toward new incentives rewarding innovation in Europe

• Main Authors: Gabrielle Nayroles (Author), Sandrine Frybourg (Author), Sylvie Gabriel (Author), Åsa Kornfeld (Author), Fernando Antoñanzas-Villar (Author), Jaime Espín (Author), Claudio Jommi (Author), Nello Martini (Author), Gérard de Pouvourville (Author), Keith Tolley (Author), Jürgen Wasem (Author), Mondher Toumi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Many established products (EPs - marketed for eight years or more) are widely used off-label despite little evidence on benefit-risk ratio. This exposes patients to risks related to safety and lack of efficacy, and healthcare providers to liability. Introducing new indications for EPs ma...