Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway

• Prif Awduron: Zhanchi Xu (Awdur), Meng Zhang (Awdur), Yu Wang (Awdur), Rui Chen (Awdur), Shiyue Xu (Awdur), Xiaohong Sun (Awdur), Yan Yang (Awdur), Zeyuan Lin (Awdur), Shaogui Wang (Awdur), Heqing Huang (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Renal tubulointerstitial fibrosis (TIF), characterized by epithelial-to-mesenchymal transition (EMT) of renal tubular epithelial cells, is the typical pathological alteration in diabetic nephropathy. Gentiopicroside (GPS), a natural compound with anti-inflammatory activity, has been demonstrated to...