Inhibition of Inflammation, Suppression of Matrix Metalloproteinases, Induction of Neurogenesis, and Antioxidant Property Make Bryostatin-1 a Therapeutic Choice for Multiple Sclerosis

• Главные авторы: Fahimeh Safaeinejad (Автор), Soheyl Bahrami (Автор), Heinz Redl (Автор), Hassan Niknejad (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Multiple sclerosis (MS) is a neurodegenerative disease characterized by inflammation and myelin damage. Pro-inflammatory cytokines, oxidative stress, high level of matrix metalloproteinases (MMPs) activity and blood-brain barrier (BBB) damage, immune-mediated destruction of myelin and neuron loss ar...