Preclinical reserpine models recapitulating motor and non-motor features of Parkinson's disease: Roles of epigenetic upregulation of alpha-synuclein and autophagy impairment

Reserpine is an effective drug for the clinical treatment of hypertension. It also induces Parkinson's disease (PD)-like symptoms in humans and animals possible through the inhibition of monoamine vesicular transporters, thus decreasing the levels of monoamine neurotransmitters in the brain. Ho...

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Main Authors: Yang Li (Author), Qiao Yin (Author), Bing Wang (Author), Tingting Shen (Author), Weifeng Luo (Author), Tong Liu (Author)
Format: Book
Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
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