Evaluation of two frailty indices, with practical application in a vaccine clinical trial

• Main Authors: Desmond Curran (Author), Melissa K. Andrew (Author), Myron J. Levin (Author), Elisa Turriani (Author), Sean Matthews (Author), Charles Fogarty (Author), Nicola P. Klein (Author), Katrijn Grupping (Author), Lidia Oostvogels (Author), Kenneth E. Schmader (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Frail older adults are at increased risk of poor clinical outcomes. Frailty assessment is therefore important in clinical trials to understand the benefits and harms of interventions. However, consensus is lacking on how frailty should be assessed. We developed a prospectively specified index using...