Targeted therapy of rheumatoid arthritis via macrophage repolarization

• Main Authors: Xu Zhou (Author), Dandan Huang (Author), Runkong Wang (Author), Mingquan Wu (Author), Liyang Zhu (Author), Wei Peng (Author), He Tu (Author), Xuangeng Deng (Author), He Zhu (Author), Zhong Zhang (Author), Xinming Wang (Author), Xi Cao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The polarization of macrophages plays a critical role in the physiological and pathological progression of rheumatoid arthritis (RA). Activated M1 macrophages overexpress folate receptors in arthritic joints. Hence, we developed folic acid (FA)-modified liposomes (FA-Lips) to encapsulate triptolide...