In vivo antitumor effect of endostatin-loaded chitosan nanoparticles combined with paclitaxel on Lewis lung carcinoma

• Main Authors: Fang Xie (Author), Rui-Lin Ding (Author), Wen-Feng He (Author), Zong- (Author), Shao-Zhi Fu (Author), Jing-Bo Wu (Author), Ling-Lin Yang (Author), Sheng Lin (Author), Qing-Lian Wen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to prepare endostatin-loaded chitosan nanoparticles (ES-NPs) and evaluate their antitumor effect when combined with paclitaxel (PTX) on Lewis lung carcinoma (LLC) mouse xenografts. ES-NPs were prepared by ionic cross-linking. Characterization of the ES-NPs included size...