Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia

• Main Authors: Isabella Pototschnig (Author), Ursula Feiler (Author), Clemens Diwoky (Author), Paul W. Vesely (Author), Thomas Rauchenwald (Author), Margret Paar (Author), Latifa Bakiri (Author), Laura Pajed (Author), Peter Hofer (Author), Karl Kashofer (Author), Nyamdelger Sukhbaatar (Author), Gabriele Schoiswohl (Author), Thomas Weichhart (Author), Gerald Hoefler (Author), Christoph Bock (Author), Martin Pichler (Author), Erwin F. Wagner (Author), Rudolf Zechner (Author), Martina Schweiger (Author)
• Format: Book
• Published: Wiley, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer‐associated cachexia (CAC) is a wasting syndrome drastically reducing efficacy of chemotherapy and life expectancy of patients. CAC affects up to 80% of cancer patients, yet the mechanisms underlying the disease are not well understood and no approved disease‐specific medic...