A novel PAX5 rearrangement in TCF3-PBX1 acute lymphoblastic leukemia: a case report

• Главные авторы: Thayana Conceição Barbosa (Автор), Bruno Almeida Lopes (Автор), Caroline Barbieri Blunck (Автор), Marcela Braga Mansur (Автор), Adriana Vanessa Santini Deyl (Автор), Mariana Emerenciano (Автор), Maria S. Pombo- (Автор)
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• Опубликовано: BMC, 2018-12-01T00:00:00Z.
• Предметы: article
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Abstract Background Chromosome translocations are a hallmark of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Additional genomic aberrations are also crucial in both BCP-ALL leukemogenesis and treatment management. Herein, we report the phenotypic and molecular cytogenetic characterizatio...