A novel PAX5 rearrangement in TCF3-PBX1 acute lymphoblastic leukemia: a case report

• Main Authors: Thayana Conceição Barbosa (Author), Bruno Almeida Lopes (Author), Caroline Barbieri Blunck (Author), Marcela Braga Mansur (Author), Adriana Vanessa Santini Deyl (Author), Mariana Emerenciano (Author), Maria S. Pombo- (Author)
• Format: Book
• Published: BMC, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chromosome translocations are a hallmark of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Additional genomic aberrations are also crucial in both BCP-ALL leukemogenesis and treatment management. Herein, we report the phenotypic and molecular cytogenetic characterizatio...