Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses.

• المؤلفون الرئيسيون: María G Alvarez (مؤلف), Graciela L Bertocchi (مؤلف), Gretchen Cooley (مؤلف), María C Albareda (مؤلف), Rodolfo Viotti (مؤلف), Damián E Perez-Mazliah (مؤلف), Bruno Lococo (مؤلف), Melisa Castro Eiro (مؤلف), Susana A Laucella (مؤلف), Rick L Tarleton (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2016-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

BACKGROUND:Chagas disease is the highest impact parasitic disease in Latin America. We have proposed that changes in Trypanosoma cruzi-specific immune responses might serve as surrogate indicators of treatment success. Herein, we addressed in a long-term follow-up study whether cure achieved after t...