Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses.

• Main Authors: María G Alvarez (Author), Graciela L Bertocchi (Author), Gretchen Cooley (Author), María C Albareda (Author), Rodolfo Viotti (Author), Damián E Perez-Mazliah (Author), Bruno Lococo (Author), Melisa Castro Eiro (Author), Susana A Laucella (Author), Rick L Tarleton (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Chagas disease is the highest impact parasitic disease in Latin America. We have proposed that changes in Trypanosoma cruzi-specific immune responses might serve as surrogate indicators of treatment success. Herein, we addressed in a long-term follow-up study whether cure achieved after t...