Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase

• Main Authors: Rita Meleddu (Author), Simona Distinto (Author), Angela Corona (Author), Enzo Tramontano (Author), Giulia Bianco (Author), Claudia Melis (Author), Filippo Cottiglia (Author), Elias Maccioni (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of 3-3-{2-[2-3-methyl-4-phenyl-2,3-dihydro-1,3-thiazol-2-ylidene]hydrazin-1-ylidene-2,3-dihydro-1H-indol-2-one derivatives has been designed and synthesized to study their activity on both HIV-1 (Human Immunodeficiency Virus type 1) RT (Reverse Transcriptase) associated functions. These der...