Response Surface Methodology (RSM) approach to formulate and optimize the bilayer combination tablet of Tamsulosin and Finasteride

• Main Authors: Muneeba Akhtar (Author), Muhammad Zaman (Author), Ahsan Zamir Siddiqi (Author), Hasan Ali (Author), Rahima Khan (Author), Muhammad Nadeem Alvi (Author), Muhammad Hammad Butt (Author), Fatma M. El-Demerdash (Author), Dalal Nasser Binjawhar (Author), Amany A. Sayed (Author), Ahmed E. Altyar (Author), Mohamed M. Abdel-Daim (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An orally administered bilayer tablet with Tamsulosin (TAM) as the sustained release (SR) and Finasteride (FIN) as immediate release (IR) was manufactured. A response surface methodology was employed to formulate bilayer tablets with individual release layers, i.e., sustained and immediate release (...