Acute promyelocytic leukemia presenting as recurrent venous and arterial thrombotic events: a case report and review of the literature

• Главные авторы: Kira MacDougall (Автор), Divya Chukkalore (Автор), Maryam Rehan (Автор), Meena Kashi (Автор), Alexander Bershadskiy (Автор)
• Формат: ‌
• Опубликовано: Greater Baltimore Medical Center, 2021-11-01T00:00:00Z.
• Предметы: article
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Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia characterized by a translocation of chromosomes 15 and 17, creating an alternation in the retinoic acid receptor-alpha (RAR-alpha) gene. This leads to excessive medullary production of promyelocytic blasts, which are...