A CREB1-miR-181a-5p loop regulates the pathophysiologic features of bone marrow stromal cells in fibrous dysplasia of bone

• Main Authors: Yu Fu (Author), Zhili Xin (Author), Ziji Ling (Author), Hanyu Xie (Author), Tao Xiao (Author), Xin Shen (Author), Jialin Lin (Author), Ling Xu (Author), Hongbing Jiang (Author)
• Format: Book
• Published: BMC, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Fibrous dysplasia (FD) is a bone marrow stromal cell (BMSC) disease caused by activating mutations of guanine nucleotide-binding protein alpha-stimulating activity polypeptide (GNAS) and is characterized by increased proliferative activity and disrupted osteogenesis of BMSCs. How...