Determination of parecoxib and valdecoxib in rat plasma by UPLC-MS/MS and its application to pharmacokinetics studies

Abstract Background The present study aimed to develop and validate a rapid, selective, and reproducible ultra-performance liquid chromatography-tandem mass spectrometry separation method for the simultaneous determination of the levels of parecoxib and its main metabolite valdecoxib in rat plasma....

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Main Authors: Mengchun Chen (Author), Wei Sun (Author), Zhe Wang (Author), Chengke Huang (Author), Guoxin Hu (Author), Yijie Chen (Author), Ledan Wang (Author)
Format: Book
Published: BMC, 2020-04-01T00:00:00Z.
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3rd Floor Main Library

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