Proteomic identification of IPSE/alpha-1 as a major hepatotoxin secreted by Schistosoma mansoni eggs.

Eggs deposited in the liver of the mammalian host by the blood fluke parasite, Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response in immune-competent mice. By contrast, in mice deprived of T-cells and incapable of producing granulomata, egg-secreted proteins (ESP)...

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Main Authors: Maha-Hamadien Abdulla (Author), Kee-Chong Lim (Author), James H McKerrow (Author), Conor R Caffrey (Author)
Format: Book
Published: Public Library of Science (PLoS), 2011-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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