Development of dry powder inhaler containing tadalafil-loaded PLGA nanoparticles

• Main Authors: Jaleh Varshosaz (Author), Somayeh Taymouri (Author), Hamed Hamishehkar (Author), Razieh Vatankhah (Author), Shadi Yaghubi (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inhalable dry powders containing poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs) were developed for the delivery of tadalafil (TAD) for treatment of life-treating pulmonary arterial hypertension. Taguchi design was employed to evaluate the effects of different formulation variables on the ph...