Short-term exposure to dimethyl fumarate (DMF) inhibits LPS-induced IκBζ expression in macrophages

• मुख्य लेखकों: Yong Zhang (लेखक), Jingshu Tang (लेखक), Yujun Zhou (लेखक), Qiong Xiao (लेखक), Qiuyu Chen (लेखक), Hongyue Wang (लेखक), Jiaqi Lan (लेखक), Lei Wu (लेखक), Ying Peng (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: The pharmacological activity of dimethyl fumarate (DMF) in treating psoriasis and multiple sclerosis (MS) is not fully understood. DMF is hydrolysed to monomethyl fumarate (MMF) in vivo, which is believed to account for the therapeutic effects of DMF. However, previous studies have provi...