Short-term exposure to dimethyl fumarate (DMF) inhibits LPS-induced IκBζ expression in macrophages

• Main Authors: Yong Zhang (Author), Jingshu Tang (Author), Yujun Zhou (Author), Qiong Xiao (Author), Qiuyu Chen (Author), Hongyue Wang (Author), Jiaqi Lan (Author), Lei Wu (Author), Ying Peng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The pharmacological activity of dimethyl fumarate (DMF) in treating psoriasis and multiple sclerosis (MS) is not fully understood. DMF is hydrolysed to monomethyl fumarate (MMF) in vivo, which is believed to account for the therapeutic effects of DMF. However, previous studies have provi...