Multimodal mucosal and systemic immune characterization of a non-human primate trachoma model highlights the critical role of local immunity during acute phase disease.

• Main Authors: Elodie Paulet (Author), Vanessa Contreras (Author), Mathilde Galhaut (Author), Ida Rosenkrands (Author), Martin Holland (Author), Matthew Burton (Author), Jes Dietrich (Author), Anne-Sophie Gallouet (Author), Nathalie Bosquet (Author), Francis Relouzat (Author), Sébastien Langlois (Author), Frank Follmann (Author), Roger Le Grand (Author), Marc Labetoulle (Author), Antoine Rousseau (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Trachoma is a leading cause of infection-related blindness worldwide. This disease is caused by recurrent Chlamydia trachomatis (Ct) infections of the conjunctiva and develops in two phases: i) active (acute trachoma, characterized by follicular conjunctivitis), then l...