Development of a LC-ESI-MRM method for the absolute quantification of orexin A in the CSF of individual mice

Sleep-wakefulness is disrupted in most neurological and psychiatric disorders. Although clinical data implicate orexin (hypocretin), a crucial sleep/wake regulatory neuropeptide, in such disorders, limited sample volumes effectively prevent quantification of cerebrospinal fluid (CSF) levels of orexi...

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Main Authors: Katherine Hopkins (Author), Soumya Mukherjee (Author), Dalia Ponce (Author), Jonathan Mangum (Author), Laura H. Jacobson (Author), Daniel Hoyer (Author)
Format: Book
Published: Elsevier, 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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