Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer

• Main Authors: Shanhui Liu (Author), Yan Tao (Author), Shan Wu (Author), Jiawei Lin (Author), Shengjun Fu (Author), Jianzhong Lu (Author), Jing Zhang (Author), Beitang Fu (Author), Erdong Zhang (Author), Jing Xu (Author), Jiaxuan Wang (Author), Lanlan Li (Author), Lei Zhang (Author), Zhiping Wang (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sanguinarine chloride (S.C) is a benzophenanthrine alkaloid derived from the root of sanguinaria canadensis and other poppy-fumaria species. Studies have reported that S.C exhibits antioxidant, anti-inflammatory, proapoptotic, and growth inhibitory effects, which contribute to it...