Cyclodextrin Stabilized Freeze-Dried Silica/Chitosan Nanoparticles for Improved Terconazole Ocular Bioavailability

• Egile Nagusiak: Nada Zaghloul (Egilea), Nada M. El Hoffy (Egilea), Azza A. Mahmoud (Egilea), Nermeen A. Elkasabgy (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-02-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

This research assesses the beneficial effects of loading terconazole, a poorly water-soluble antifungal drug in silica/chitosan nanoparticles (SCNs) for ocular delivery. Nanoparticles were fabricated by the simple mixing of tetraethyl ortho silicate (TEOS) and chitosan HCl as sources of silica and n...