Capsaicin protects cardiomyocytes against lipopolysaccharide-induced damage via 14-3-3γ-mediated autophagy augmentation

• Hauptverfasser: Yang Qiao (Verfasst von), Liang Wang (Verfasst von), Tianhong Hu (Verfasst von), Dong Yin (Verfasst von), Huan He (Verfasst von), Ming He (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background: The myocardium is susceptible to lipopolysaccharide (LPS)-induced damage in sepsis, and cardiac dysfunction is a leading cause of mortality in patients with sepsis. The changes in cardiomyocyte autophagy in sepsis and the effects and mechanism of action of capsaicin (Cap) remain unclear....